For years, Alzheimer’s conferences were like the obituary pages in the local newspaper: It’s where clinicians and researchers in the field went to find out the names of the latest promising drugs to die. Between 1998 and 2017 alone, 146 clinical trials of new Alzheimer’s drugs failed…
The big potential benefit (of new drugs), say Alzheimer’s experts, lies in using these drugs, or others soon to come, in conjunction with a second recent development in the field: diagnostic blood tests that can identify the presence of Alzheimer’s-associated proteins…. Scientists believe that in a few years clinicians may be able to use them to make quick, early diagnoses cheaply, even before patients show any outward symptoms. That suggests a new strategy against the disease: GPs could screen otherwise healthy people for early-stage Alzheimer’s and treat them with drugs that slow the progress of the disease before major damage has occurred. The hope is that eventually, Alzheimer’s will no longer be a terminal disease but a chronic one that can be managed with drugs and perhaps be staved off indefinitely.
Full article also covers the history of the disease, why it was so hard to develop effective drugs, and how PET scans (to detect amyloid and tau in living people) were a game-changer. And remember, this is just the start — the future will only bring better treatments. 4,400 words: https://www.newsweek.com/2023/10/20/can-we-prevent-alzheimers-scientists-say-new-tests-treatments-game-changer-1832957.html.
Bonus: an item from FutureCrunch:
Ten people died from unprovoked shark attacks globally in 2023, a slight uptick over the five-year average. This makes sharks less dangerous than lawn mowers, ladders, champagne corks, jet skis, and lightning strikes.
Guess which one of those things got an entire article in ABC News?
Laugh / learn links log 